Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes. However, ...

Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study ...

Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

Identifying a few key genes within the vastness of the human genome was once akin to finding the proverbial needle in a haystack. But with the introduction of functional genomic screening, scientists ...

When COVID first hit, waiting days for laboratory results from an ultrasensitive polymerase chain reaction (PCR) test was commonplace. Faster tests usable by anyone, anywhere, later became widely ...

CRISPR Therapeutics has reported reductions in triglycerides and LDL cholesterol of more than 80% after a single dose of its in vivo liver editing prospect CTX310, encouraging the company to forge ...

WEST LAFAYETTE, Ind. — More than a decade ago, scientists harnessed a bacterial molecular machine that identifies and cuts specific sections of DNA, revolutionizing the ability to edit genes and ...

For years, the CRISPR-Cas9 genome technology has been reshaping genetic engineering, a precision tool to transform everything from agriculture to medicine. With its incredible efficiency, this ...

A screening approach has been designed to measure efficiency and specificity for thousands of CRISPR-associated transposons ...