Chimeric antigen receptor (CAR) T-cell therapy-associated immune-related adverse events (CirAEs) were associated with a high ...

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...

Measuring CD4 T-cells is important in helping healthcare providers determine the stage and possible complications of HIV infection. While they are no longer used to determine when HIV therapy should ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...

The ratio of CD4 to CD8 T cells in the blood-a marker of immune system health and associated with mortality risk in the general population-is an independent predictor of coronary heart disease in ...

Acute graft-versus-host disease (aGVHD) is a life-threatening complication after allogeneic hematopoietic stem cell ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Most of these treatments are based on CD8 T lymphocytes, ''killer cells'' able to eliminate diseased cells. A team from the University of Geneva (UNIGE) has explored an alternative approach involving ...

A phase I trial of intratumoral adenovirus-interleukin-12 (IT-ADV/IL-12) and atezolizumab in metastatic non-small cell lung cancer (NSCLC) progressed on first-line immunotherapy.