The diagram illustrates the key stages of protein synthesis in a eukaryotic cell. It begins with transcription to produce pre-mRNA in the nucleus (1), followed by post-transcriptional modification (2) ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Postdoctoral researcher Urmila Sehrawat discusses her work at Memorial Sloan Kettering Cancer Center on translational machinery and novel cancer therapeutics.

The precise synthesis of proteins is considered essential for cellular function. Now, a team led by LMU biologists Dr. Benjamin Brandt and Professor Hans-Henning Kunz has demonstrated for the first ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

In today’s rapidly evolving scientific landscape, eliminating barriers to progress is more critical than ever. Precision medicine and targeted therapies hold great promise but are dependent on the ...

Researchers discover the largest protein yet identified in biology, all thanks to an investigation of a marine alga’s creates toxin synthesis. In a recent study, researchers at UC San Diego’s Scripps ...

Constructive Bio, a leading synthetic biology company based in Cambridge, has recruited world-class life science veteran Jim ...