T cells are central mediators of autoimmune disease pathogenesis, yet their functional states are not defined solely by antigen recognition or canonical ...
All patients with autoimmune hemolytic anemia in a small study initially achieved remission, though two eventually relapsed, ...
In a discussion hosted by Dr. Zachary Roberts, Executive Vice President of R&D and Chief Medical Officer at Allogene Therapeutics, leading rheumatologists Dr. Chris Wincup of King’s College Hospital ...
MedPage Today on MSN
Autoimmune Anemia Is the Latest Condition Found Responsive to CAR-T Therapy
Eleven patients with refractory autoimmune hemolytic anemia (AIHA) were all brought into drug-free remission with CAR T-cell ...
China: CAR T-cell therapy, already in use for certain B-cell–driven autoimmune diseases such as lupus, has now demonstrated ...
Immune checkpoint pathways regulate T cell function and play pivotal roles in the treatment of both cancer and autoimmune diseases. One key component of these pathways is Lymphocyte Activation Gene 3 ...
Autoimmune diseases share the same core pathology despite their differing clinical manifestations: dysregulated B and T cell activity. B cells contribute to disease progression by secreting ...
Cue Biopharma, Inc. has announced that it has received positive Pre-Investigational New Drug (Pre-IND) feedback from the FDA regarding its planned first-in-human trial for CUE-401, a novel bispecific ...
Neurodegenerative diseases, traditionally viewed as driven by neuronal decline, are increasingly recognized to involve ...
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