The discovery of a new preclinical compound with strong antifungal activity against multidrug-resistant pathogens is described in Nature. The drug, named mandimycin, is a member of a known family of ...

Invasive fungal infections are a substantial medical concern, particularly in immunocompromised patients. As medical advances increase the size of this population, invasive fungal infections will ...

The pharmacology, bioavailability and pharmacokinetics, clinical efficacy, and adverse effects of caspofungin acetate are reviewed. Caspofungin acetate is an echinocandin with fungicidal activity ...