Kickoff from L&N Federal Credit Union Stadium in Louisville, Ky., is at 7:30 p.m. ET. The Cardinals are 1.5-point favorites ...

The Clemson Tigers upset the Louisville Cardinals in a Week 12 ACC college football game on the road. Here are the highlights ...

Clemson is all but certain to make it 21 straight years in a bowl game after an upset win over Louisville. Here's who and ...

Clemson looks to make a bowl game and spoil Louisville's CFP hopes with a win in Week 12. Here's what to know about the game ...

Dabo Swinney and the Clemson Tigers play a rare Friday night game against Louisville in Week 12. Here are the TV announcers ...

No. 20 Louisville loses to the Clemson Tigers in one of the most frustrating ways possible to fall to 7-3 on the season.

However, that hasn't led to the amount of wins Tigers fans have come to expect for coach Dabo Swinney. Clemson will need to ...

The 15th-ranked Louisville Cardinals look to keep their conference championship hopes alive when they battle the Clemson ...

L&N Federal Credit Union Stadium is the location where the Louisville Cardinals (7-1) will play the Clemson Tigers (3-5) on ...

The Clemson Tigers earned a 20-19 victory over the Louisville Cardinals in Week 12 of the college football season. Here are ...

Louisville lost this game because of missed opportunities. However, no game comes down to a handful of mistakes or misses. It ...

Clemson vs Louisville predictions and college football picks for Friday4. Cade Klubnik & Co. upend the Cardinals.